Orally, cranberry is usually well tolerated and certainly at a normal intake of 1-2 cups/day. However, in very large doses, for example 12-17 cups/day of juice, cranberry can cause gastrointestinal upset and diarrhea. Nausea, vomiting, and diarrhea have also been reported with consumption of lower doses of cranberry juice cocktail, 2 cups/day, equivalent to about 4 oz. cranberry juice, for several weeks in pregnant women. Consuming more than 4 cups/day over a prolonged period of time might also increase the risk of uric acid kidney stone formation